September 28, 2016 Colloquium

Locating Mutations in the Human PCSK6 Gene using Whole Genome Sequencing

Jack Warner, Millersville University

Abstract: In previous studies the PCSK6 gene was linked to asymmetrical development of the heart. Mutations in this gene tie into the failure of atrial separation which is one of the most common type of congenital heart disease (CHD). This project seeks to find novel mutations in PCSK6 in atrial septal defect patients using whole genome sequencing. We studied the average coverage of the exomes and genomes and found that the current depth was inadequate to produce significant results.

Location: Wickersham 201, Millersville University

Time: 4:00 - 5:00pm