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Millersville University Biology Department |
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Education:
B.A., Wellesley College
Ph.D., Brown University
Courses Taught:
BIOL 100 -- General Biology
BIOL 462 -- Molecular Biology
BIOL 466 -- Molecular and Celluar Techniques
BIOL 264 / 265 -- Frontiers in BioMolecular Science
BIOL 472 -- Senior Seminar in Molecular Biology
Cell Biology Labs
Genetic Laboratories
Areas of Specialization:
Molecular, Developmental and Cell Biology.
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Research Interest(s):
Using molecular-based methods such as Southern/Northern
hybridizations, polymerase chain reaction (PCR), RFLP
analysis, DNA sequencing, and recombinant DNA technology,
I study genes whose DNA is amplified during the larval
development of a fungal gnat called Sciara coprophila.
This is used as a model system to learn more about the
regulation of eukaryotic DNA replication--a topic critical
to our understanding of cancer. I am also collaborating
with Dr. Moné on a project to study the population
dynamics and relatedness of viruses that infect and
kill fresh water algae. Other projects of interest are
the development of laboratory exercises for General
Biology and Molecular and Cellular Techniques. This
research requires attention to detail and precision.
Students should have a strong interest in their research
topic and be willing and able to learn more about techniques
on an independent basis.
Students will also experience the joys of collecting
and culturing these organisms for study.
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Selected Publication(s):
DiBartolomeis, S.M. and Moné, J.P. (2003). Apoptosis: A four-week laboratory investigation for advanced molecular and cellular biology students. Cell Bio. Educ. 2: 275-295.
2002.
Molecular analysis of the Drosophila miniature-dusky
(m-dy) gene complex: m-dy mRNAs encode transmembrane
proteins with similarity to C. elegans cuticulin. Mol.
Genet. Genomics 267: 564-576. (with B. Akten, G.
Genova, M.A. Roberts, and , F.R Jackson).
2001. Maintenance of the DNA puff expanded state is
independent of active replication and transcription.
Chromosoma. 110: 186-196. E.H. Mok, H.S. Smith,
S.M. DiBartolomeis, A.W. Kerrebrock, L.J. Rothschild,
T.S. Lange, and S.A. Gerbi.
1993. Developmental progression of DNA puffs in Sciara
coprophila: Amplification and Transcription Developmental
Biology 160: 73-84. (with N. Wu, C. Liang, H. Smith
and S. Gerbi)
1993. DNA amplification in DNA puff II/9A of Sciara
coprophila. Cold Spring Harbor Sym. Quant. Biol.,
5:487-494 (with S. Gerbi, C. Liang, N. Wu, B. Bienz-
Tadmor, H. Smith and F. Urnov)
1992. A superfamily of Drosophila
satellite related (SR) DNA repeats restricted to the
X chromosome euchromatin. Nuc.Acids Res. 20:
1113-1116. (with K. Tartof and F. Jackson).
1991. Mutational analysis of the Drosophila
miniature dusky (m-dy) locus: Effects on cell size
and circadian rhythms. Genetics 128: 571-582.
(with L. M. Newby, et.al..)
1989. Molecular characterization of DNA puff II/9A genes
in Sciara coprophila. J. Molec. Biol. 210:
531-540. (with S.A. Gerbi).
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