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Phosphinate-containing rhodol and fluorescein scaffolds for the development of bioprobes.

Student Author(s): Good, Gillian N.
Faculty Author(s): -
Department: CHEM
Publication: Chemical Communications
Year: 2019
Abstract: A series of phosphinate-containing rhodol and fluorescein dyes are disclosed. These new fluorophores increase the color palette of phosphinate-based xanthenes in the far-red spectral region. The new chemical functionality of these scaffolds is leveraged to produce a sensitive, no-wash imaging probe for cellular esterase activity. The reported phosphinate-containing dyes provide platforms for the further development of imaging probes and self-reporting delivery vehicles. [ABSTRACT FROM AUTHOR] Copyright of Chemical Communications is the property of Royal Society of Chemistry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Link: Phosphinate-containing rhodol and fluorescein scaffolds for the development of bioprobes.

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