Publications

Corneal endothelial cell density in patients receiving chemotherapy.

Faculty Author(s): Gallagher, Shawn
Student Author(s): -
Department: PHYS
Publication: Cutaneous & Ocular Toxicology
Year: 2021
Abstract: This study aimed to determine if the corneal endothelium was affected by chemotherapy. Chemotherapy patients were recruited to undergo specular microscopy before treatment and again at 1- and 2-year follow-up visits. One eye per patient, per follow-up, was selected for comparison to baseline. Forty-six volunteers completed baseline and at least one follow-up assessment. From 51 eyes, there was no significant change in endothelial cell density for 41 eyes assessed at one year (MD = 0.73%, 95% CI −1.33 to 2.78%) and 18 eyes at two years (MD = 0.31%, 95% CI −3.53 to 4.15%). Although other studies have shown that chemotherapy can adversely affect the corneal epithelium, this study showed no measurable change in endothelial cell density. [ABSTRACT FROM AUTHOR] Copyright of Cutaneous & Ocular Toxicology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Link: Corneal endothelial cell density in patients receiving chemotherapy.