Student Scholars & Faculty Mentors
Projects funded by our internal grants program. Search the table to find students or faculty mentors that share in your interests, and could help you achieve your goals in research, creative activity, or service.
Synthetic Studies Toward 3,4-Dihydro-2(1H)-Quinolinone Derivatives
Name: Drager,
Advisor: Steven Kennedy
Department: CHEM
Award: Noonan Endowment
Abstract: Derivatives of 3,4-dihydro-2(1H)-quinolinones are the pathway to a class of successful natural product antibiotics. Hunanamycin A contains this structure and has shown antibacterial activity against gram negative pathogens such as Salmonella and Escherichia coli. Hunanamycin A started the interest and search for a synthetic pathway to 3,4-dihydro-2(1H)-quinolinones and their potential derivatives. Derivatives of the structure could also allow access to intermediates with increased molecular complexity or biological activity